Guidelines

What is the mortality rate of Lassa fever?

What is the mortality rate of Lassa fever?

Approximately 15%-20% of patients hospitalized for Lassa fever die from the illness. However, only 1% of all Lassa virus infections result in death. The death rates for women in the third trimester of pregnancy are particularly high.

How many people died from Lassa virus?

An estimated 100,000 to 300,000 infections of Lassa fever occur annually, with approximately 5,000 deaths.

Can Lassa fever be cured?

What is the treatment for Lassa fever? Ribavirin given intravenously and early in the course of illness is an effective treatment, in addition to support of fluid and electrolytes, oxygenation, and blood pressure.

Who is most at risk for Lassa fever?

Individuals at greatest risk of Lassa virus infection are those who live in or visit endemic regions, including Sierra Leone, Liberia, Guinea, and Nigeria and have exposure to the multimammate rat. Risk of exposure may also exist in other west African countries where Mastomys rodents exist.

What kind of rat causes Lassa fever?

The animal reservoir, or host, of Lassa virus is a rodent of the genus Mastomys, commonly known as the “multimammate rat.” Mastomys rats infected with Lassa virus do not become ill, but they can shed the virus in their urine and faeces.

What risk group is Lassa virus?

SPECIAL HAZARDS: Work with, or exposure to rodents that are naturally or experimentally infected represents a risk of human infection. RISK GROUP CLASSIFICATION: Risk Group 4(22).

Do all rats cause Lassa fever?

Lassa fever is a viral infection carried by the multimammate rat Mastomys natalensis (M. natalensis). This is one of the most common rodents in equatorial Africa, found across much of sub-Saharan Africa. Lassa fever mainly occurs in Sierra Leone, Liberia, Guinea, and Nigeria.

What type of rat causes Lassa fever?

The reservoir, or host, of Lassa virus is a rodent known as the “multimammate rat” (Mastomys natalensis). Once infected, this rodent is able to excrete virus in urine for an extended time period, maybe for the rest of its life.