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What is hydroxypropyl beta cyclodextrin?

What is hydroxypropyl beta cyclodextrin?

2-Hydroxypropyl-β-cyclodextrin (HP-β-CD) is a chemically modified cyclic oligosaccharide produced from starch that is commonly used as an excipient. Although HP-β-CD has been suggested as a potential adjuvant for vaccines, its immunological properties and mechanism of action have yet to be characterized.

What is 2 hydroxypropyl cyclodextrin Hbcd?

Product Description. 2-Hydroxypropyl-β-cyclodextrin (HP-β-CD) is a cyclic oligosaccharide containing seven D-(+)-glucopyranose units that is widely used to improve the aqueous solubility of various compounds, especially those containing a phenyl group.

What is beta cyclodextrin?

β-Cyclodextrin is a cyclic oligosaccharide consisting of seven glucose subunits joined by α-(1,4) glycosidic bonds forming a truncated conical structure. It is widely used in food, pharmaceutical, cosmetics, and chemicals industries.

What is beta cyclodextrin good for?

Cyclodextrins, and expecially beta ones, are widely used in the pharmaceutical field for their ability of improving the solubility and the stability of drugs by complex formation at the solid state.

Is beta cyclodextrin safe?

Most of the hydrophilic derivatives of natural cyclodextrins like 2-hydroxypropyl-β-cyclodextrin and sulphobutylether-β-cyclodextrin are considered safe for parenteral administration. Higher dose of cyclodextrins may be harmful.

What is 2-hydroxypropyl-β-cyclodextrin used for?

2-Hydroxypropyl-β-cyclodextrin (HP-β-CyD) is a cyclic oligosaccharide that is widely used as an enabling excipient in pharmaceutical formulations, but also as a cholesterol modifier.

Is 2-hydroxypropyl-β-cyclodextrin safe?

HP-beta-CD has been shown to be well tolerated in humans, with the main adverse event being diarrhoea and there have been no adverse events on kidney function, documented to date.

Is beta-cyclodextrin safe?

Is 2 hydroxypropyl beta cyclodextrin safe?

What vitamin removes plaque from arteries?

Niacin, or Vitamin B3, is the best agent known to raise blood levels of HDL, which helps remove cholesterol deposits from the artery walls.