What is effective filtration pressure?
Effective filtration pressure is the final force of water and solute across the membrane of glomerulus. – Glomerular blood hydrostatic pressure: It is due to difference in diameters of afferent and efferent arterioles (GHP) = 60mm of Hg.
What is the relationship between filtration pressure and filtration rate?
The glomerular filtration rate is directly proportional to the pressure gradient in the glomerulus, so changes in pressure will change GFR. GFR is also an indicator of urine production, increased GFR will increase urine production, and vice versa.
What is filtration pressure?
The net filtration pressure is the outward pressure minus the inward pressure. Figure of a glomerular capsule with glomerular hydrostatic pressure, blood colloid osmotic pressure, and capsular hydrostatic pressure.
What factors influence effective filtration pressure?
Glomerular hydrostatic pressure is determined by, Arterial pressure, Afferent & Efferent arteriolar resistance. In turn, each parameter affects GFR.
What is the formula for net filtration pressure?
NFP
Net filtration pressure (NFP) = glomerular blood hydrostatic pressure (GBHP) – [capsular hydrostatic pressure (CHP) + blood colloid osmotic pressure (BCOP).
What is effective filtration process?
Effective filtration pressure (EFP) refers to the net driving forces for water and solute transport across the glomerular membrane.
What are the three factors that regulate glomerular filtration rate?
Three factors regulate glomerular filtration rate (GFR). These three factors are decrease in systemic blood pressure, normal systemic blood pressure, and increase in systemic blood pressure. The body must maintain homeostasis. Hence, the body will respond to each factor.
What would increase the glomerular filtration rate?
blood pressure
Increased blood volume and increased blood pressure will increase GFR. Constriction in the afferent arterioles going into the glomerulus and dilation of the efferent arterioles coming out of the glomerulus will decrease GFR.
What forces promote filtration?
The forces that govern filtration in the glomerular capillaries are the same as any capillary bed. Capillary hydrostatic pressure (Pc) and Bowman’s space oncotic pressure (πi) favor filtration into the tubule, and Bowman’s space hydrostatic pressure (Pi) and capillary-oncotic pressure (πc) oppose filtration.
What is the normal net filtration pressure?
10mm Hg
NET FILTRATION PRESSURE (NFP) is the total pressure that promotes filtration. To calculate NFP, we subtract the forces that oppose filtration from the GBHP. A normal NFP (using the figures mentioned) would be: NFP=55-(15+30)=55-45=10mm Hg.
What increases Net filtration pressure?
An increase in renal arterial pressure (or renal blood flow) causes an increase in GFR. A reduction in renal arterial pressure (or renal blood flow) will have the opposite effect (1).