What does a positive EBV AB VCA IgG mean?
The presence of VCA IgG antibodies indicates that an EBV infection has occurred at some time recently or in the past. The presence of VCA IgM antibodies and the absence of antibodies to EBNA mean that the infection has occurred recently. The presence of antibodies to EBNA means that the infection occurred in the past.
How long does EBV IgG stay positive?
Viral capsid antigen (VCA) Anti-VCA IgM appears early in EBV infection and usually disappears within four to six weeks. Anti-VCA IgG appears in the acute phase of EBV infection, peaks at two to four weeks after onset, declines slightly then persists for the rest of a person’s life.
What is EBV VCA IgA positive?
A positive serum IgA VCA titer indicates previous repeated infection by the virus or frequent reactivation of latent EBV in B cells. This has been used as a screening tool to identify subjects at high risk of NPC,4,5 as well as being a diagnostic criteria for undifferentiated NPC.
What is EBV AB VCA?
Presence of VCA IgM antibodies indicates recent primary infection with Epstein-Barr virus (EBV). The presence of VCA IgG antibodies indicates infection sometime in the past. Antibodies to EBNA develop 6 to 8 weeks after primary infection and are detectable for life.
What is a good IgG level?
Normal Ranges Adult: IgG 6.0 – 16.0g/L. IgA 0.8 – 3.0g/L. IgM 0.4 – 2.5g/L.
What does EBV AB VCA, IgG stand for?
EBV-VCA, IgG is an antibody (protein) that is produced by the body in an immune response to an Epstein-Barr virus antigen. EBV stands for Epstein-Barr virus. Epstein-Barr virus is a virus that typically causes a mild to moderate illness.
When does early antigen ( EA ) IgG appear in EBV?
Anti-VCA IgG appears in the acute phase of EBV infection, peaks at two to four weeks after onset, declines slightly then persists for the rest of a person’s life. Early antigen (EA) Anti-EA IgG appears in the acute phase of illness and generally falls to undetectable levels after three to six months. In many people, detection of antibody
What are the results of a VCA IgG test?
Please refer to this interpretation chart: VCA IgG VCA IgM EBNA IgG Interpretation Negative Negative Negative No previous exposure Positive Positive Negative Recent infection Positive Negative Positive Past infection Positive Negative Negative See note*
Which is the best Antibody to test for EBV?
In cases where EBV is suspected but the heterophile antibody is not detected, an evaluation of EBV-specific antibodies (eg, IgM and IgG antibodies to EBV viral capsid antigen: VCA) and antibodies to EBV nuclear antigen (EBNA) may be useful.