What does a high HSV 2 IgG mean?

What does a high HSV 2 IgG mean?

A positive result strongly suggests a recent or past HSV infection. The person may be capable of transmitting the virus to others. A small percentage of positive HSV-2 IgG results may be false-positive. 1. Further testing may be appropriate for patients with a low or unexpected positive HSV-2 IgG result.

How long does it take for HSV 2 IgG to become positive?

The time required for the development of IgG antibodies following HSV infection varies from 21 to over 42 days with most individuals having detectable IgG 21–28 days after exposure to the infection and probably lasting for life.7–,9 IgM antibodies are usually detectable 9–10 days after exposure and last 7–14 days.

What is the normal range of herpes simplex virus?

Component Reference Interval
Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgG Less than 0.80: Negative
0.80 – 0.99: Equivocal-Repeat in 10-14 days may be helpful.
Greater than 0.99: Positive – May indicate a current or previous HSV infection.
Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgM Less than 0.90: Negative

Should I be worried if I test positive for HSV 1?

Positive/Abnormal. HSV was found in your sample. It may mean you have an active infection (you currently have sores), or were infected in the past (you have no sores). If you tested positive for HSV, talk to your health care provider. While there is no cure for herpes, it hardly ever causes serious health problems.

What is normal IgG range?

Normal Ranges Adult: IgG 6.0 – 16.0g/L. IgA 0.8 – 3.0g/L. IgM 0.4 – 2.5g/L.

How long does it take for HSV IgM to convert to IgG?

First, IgM antibodies typically become detectable about 10 to 21 days post infection, with IgG-class antibodies developing around the same time.

What does herpes IgG positive mean?

If you test positive for IgG but not IgM, you have probably been infected for at least two months. If you test positive for IgG and IgM or just IgM alone, then it’s likely that you have a new infection.

What should herpes simplex virus type 2 IgG index be?

CDC guidelines recommend confirmatory testing of sera with low-positive indices (1.10-3.50) in the HerpeSelect® (HSLT) HSV-2 IgG screening assay. To determine if this recommendation is adequate for our patient population, we reviewed HSLT HSV-2 IgG screening indices for 262 screen-positive sera (ind …

Can you test for herpes simplex virus type 1?

Not recommended for herpes simplex virus (HSV) testing; IgM lacks adequate predictive value for acute infection. If pursing antibody testing, refer to Herpes Simplex Type 1 and Type 2 Glycoprotein G-Specific Antibodies, IgG by CIA ( 0051152 ).

Can a IgM be used to diagnose genital herpes?

Currently available IgM serologic tests can be falsely positive and should not be used to diagnose genital herpes. • Type-specific serologic tests provide qualitative results. Thus, the exact value does not relate to the severity, re- cency, or other clinical characteristics of the individual’s infection.

What kind of antibodies does herpes simplex virus have?

Refrigerated. Refer to individual components. CSF (refer to Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgG & IgM (CSF) with Reflex to Type 1 & 2 Glycoprotein G-Specific Ab, IgG, test code 0050364).Refer to individual components.