What type of drug is cetuximab?
Cetuximab is in a class of medications called monoclonal antibodies. It works by slowing or stopping the growth of cancer cells.
How well does cetuximab work?
Cetuximab also has activity as monotherapy in patients with recurrent and/or metastatic SCCHN who had failed platinum-based chemotherapy,. with a 12.6% response rate, disease control rate of 46%, and median response duration of ~ 6 months.
Can cetuximab cure cancer?
Erbitux Offers ‘cure’ Potential To 3 Out Of 4 Advanced Colon Cancer Patients – But Conditions Apply. Researchers have narrowed down the conditions in metastatic colorectal cancer (mCRC) where treatment with the targeted biologic therapy Erbitux (cetuximab) is most likely to succeed.
What is the cost of cetuximab?
The Costs of Cancer Treatments
| Drug (brand name) | Regimen | Total cost ‡ |
|---|---|---|
| Cetuximab (Erbitux) | Loading: 400 mg/m 2 ; maintain: 250 mg/m 2 /wk | $80 352 |
| Bevacizumab (Avastin) | 10 mg/kg every 14 d | $90 816 |
| Erlotinib (Tarceva) | 150 mg daily | $15752 |
| Sorafenib (Nexavar) | 400 mg twice a day | $34373 |
Is cetuximab chemo or immunotherapy?
Immunotherapy with monoclonal antibodies, such as pertuzumab and cetuximab, may help the body’s immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.
Can cetuximab shrink Tumours?
Early Tumor Shrinkage in Colorectal Cancer Suggests Long-Term Cetuximab Benefit. Colorectal cancer patients who have early tumor shrinkage after first-line treatment with chemotherapy plus cetuximab may be more likely to have long-term response to therapy, according to an analysis of two large clinical trials.
What is Erbitux used to treat?
Cetuximab is used to treat a certain type of cancer of the colon (large intestine) or rectum. This medication is also used to treat head and neck cancer. Cetuximab works by slowing or stopping the growth of cancer cells.
When is cetuximab used?
Cetuximab (Erbitux®) is a targeted therapy drug. It is used to treat cancer of the bowel (colon and rectum), or head and neck.
Does cetuximab cause hair loss?
With some of the newer types of treatments, such as erlotinib, cetuximab, panitumumab, sorafenib and vemurafenib, the hair progressively can become thin, curly and dry, but it does not completely fall out. In these cases, the thinning is usually temporary.
What are the side effects of 5FU?
Common side effects of 5FU
- Risk of infection. This treatment can reduce the number of white blood cells in your blood.
- Bruising and bleeding.
- Anaemia (low number of red blood cells)
- Feeling sick.
- Diarrhoea.
- Sore mouth and throat.
- Loss of appetite.
- Changes to your taste.
What are the side effects of cetuximab?
The following side effects are common (occurring in greater than 30%) for patients taking cetuximab:
- Skin reactions: In most people, this will present as an acne like rash and will develop within the first 2 weeks of therapy.
- Generalized weakness, fatigue.
- Weight loss and poor appetite.
- Diarrhea.
- Nausea and Vomiting.