What is chemotherapy of tuberculosis?
The anti-tuberculosis therapy is a unique, two-phased chemotherapy consisting of initial intensive phase with multiple drugs (three or more) and continuation phase with two or three drugs.
Can chemotherapy cause tuberculosis?
The British National Institute for Health and Care Excellence (NICE) recommendations state that people who “have a haematological malignancy”, “are having chemotherapy” and ”have had a gastrectomy” (for gastric cancer or other reasons) are at increased risk of developing TB, but they do not provide any specific …
What is the rationale of giving combined chemotherapy for tuberculosis?
Treating a tuberculosis patient with a monotherapy of rifampicin rapidly leads to resistance to the drug even if it is given for short periods only. In combination drugs, the presence of isoniazid reduces the probability for the survival of rifampicin-resistant mutants.
What is chemotherapy Slideshare?
Definition Chemotherapy & Antibiotics: • Chemotherapy: Chemotherapy is the treatment of infections by substances which destroy or suppress bacteria and other microorganism. The substances / Agents used may natural synthetic or semi – synthetic in nature.
What are second line drugs for TB?
Second line drugs are the TB drugs that are used for the treatment of drug resistant TB. The second line drugs include levofloxacin, moxifloxacin, bedaquiline, delamanid and linezolid. There is also pretomanid which is a new second line drug recommended in 2019 for the treatment of drug resistant TB.
What is chemotherapy process?
Overview. Chemotherapy is a drug treatment that uses powerful chemicals to kill fast-growing cells in your body. Chemotherapy is most often used to treat cancer, since cancer cells grow and multiply much more quickly than most cells in the body. Many different chemotherapy drugs are available.
What are the two formulations of anti TB drugs?
Currently, the WHO Model List of Essential Drugs includes two-drug formulations (INH + RIF and INH + ethambutol), three-drug formulations (INH + RIF + ethambutol and INH + RIF + pyrazinamide) and a four-drug formulation (INH + RIF + ethambutol + pyrazinamide) [13].
How many stages of active TB treatment are there?
The standard six month course of treatment consists of two phases. The first phase lasts two months and is called the intensive phase. The second phase lasts four months and is called the continuous phase.
What is the principle of chemotherapy?
The goal of chemotherapy is to destroy cancer cells. Traditional chemotherapies work by killing cells that divide rapidly. But as they wipe out fast-growing cancer cells, they can also damage fast- growing healthy cells. Damage to healthy blood cells can lead to side effects such as fatigue or infection.
What are the five classes of chemotherapy drugs?
Cancer chemotherapy agents are classified according to their chemical nature and function. Some of the well known classes of cancer chemotherapy agents include alkylating agents, plant alkaloids, antimetabolites, anthracyclines, topoisomerase inhibitors and corticosteroids.
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How are cookies used in chemotherapy of tuberculosis?
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Which is the best treatment for tuberculosis ( TB )?
The key to successful elimination of tuberculosis (TB) is treatment of cases with optimum chemotherapy. Poor chemotherapy over time has led to drug-resistant disease.
Who is the best doctor for chemotherapy of tuberculosis?
CHEMOTHERAPY OF TUBERCULOSIS S.SEETARAM SWAMY, M.Pharm., Asst. professor, Dept. of Pharmaceutical Chemistry, Chilkur Balaji College of Pharmacy. E-mail:[email protected]