Is benign metastasizing leiomyoma cancer?
INTRODUCTION: Benign metastasizing leiomyoma(BML) is a rare tumor primarily affecting the lungs of late reproductive-aged women with a history of uterine leiomyomas.It has benign histological features, though it metastasizes (biological behavior of malignancy).
What is benign metastasizing leiomyoma?
Benign metastasizing leiomyomas are rare tumors composed of benign smooth muscle cells derived from uterine leiomyomas presenting in an extrauterine site. They are most often encountered in premenopausal women with a known history of leiomyomas [2, 8].
What is BML disease?
Benign metastasizing leiomyomatosis (BML) is a rare disease that typically occurs in women of reproductive age with a history of uterine leiomyomata who have been treated with hysterectomy. Most often the patients are asymptomatic with pulmonary nodules found incidentally on chest imaging.
Do leiomyomas spread?
The leiomyomas can metastasize to several organs, the lungs being the most common target. In very few cases, other systems or organs, such as the skin, bladder, esophagus, liver, and bone, can also be affected by the condition [2, 3].
What are benign smooth muscle tumors called?
A leiomyoma, also known as fibroids, is a benign smooth muscle tumor that very rarely becomes cancer (0.1%). They can occur in any organ, but the most common forms occur in the uterus, small bowel, and the esophagus.
Can you still get pregnant after a myomectomy?
Is pregnancy possible after a myomectomy? In most cases pregnancy after myomectomy is possible. “But the chances depend on the age of the woman, the number, size and location of fibroids for which surgery was done and other associated factors,” says Dr.
Can fibroids grow in the lungs?
Benign metastasizing leiomyoma (BML) is a rare disease that occurs in middle-aged women with a history of uterine myomas. The most common location of BML is the lungs.
Can fibroids spread to the lungs?
Pulmonary benign metastasizing leiomyoma (BML) is a rare event characterized by benign soft-tissue tumors that occur when uterine leiomyomas metastasize to the lung.
Is papilloma a benign tumor?
Papillomas are benign growths. This means that they do not grow aggressively and they do not spread around the body. The growths only form in certain types of tissue, although these tissues occur all over the body. Papillomas are often known as warts and verrucae when they reach the skin.
Are benign tumors smooth?
Leiomyomas are benign tumors of smooth, or involuntary, muscle. Leiomyomas can arise almost anywhere in the body in either men or women because they start in tissues as widespread, for example, as blood vessels or intestine. The most common of these is the fibroid tumor that often develops in the uterus.
How can I get pregnant fast after myomectomy?
Here are a few tips to keep in mind that may help you have a successful pregnancy after myomectomy.
- Consuming a balanced diet. “Soon after surgery, you should consume a healthy diet that is rich in protein.
- Tracking your menstrual cycles.
- Assessing Tubal Factors.
- Resuming Exercise.
What happens if you get pregnant too soon after a myomectomy?
Pregnancy after myomectomy may increase the risk of intrauterine adhesions, miscarriage, preterm birth, abnormal placentation, cesarean section, and uterine rupture [5,6].
Is there such a thing as benign metastasizing leiomyoma?
Benign metastasizing leiomyoma (BML) is a rare and poorly characterized disease affecting primarily premenopausal women. Asymptomatic patients are often diagnosed incidentally by radiographs or other lung-imaging procedures performed for other indications, and the diagnosis is eventually confirmed b …
Are there any rare types of leiomyomata in humans?
Rare growth patterns of uterine leiomyomata have been observed which include benign metastasizing leiomyoma (BML), disseminated peritoneal leiomyomatosis (DPL), intravenous leiomyomatosis (IVL), retroperitoneal leiomyomatosis (RPL) and parasitic leiomyoma (PL).
Which is more common, BML or Intravenous leiomyomatosis?
Intravenous leiomyomatosis (IVL) is historically less common than BML. Even more of an oddity, IVL can extend into the cardiopulmonary system including the right atrium, right ventricle, and pulmonary arteries. When this manifestation of IVL occurs, IVL is then termed intracardiac leiomyomatosis (ICLM).
Can a hysterectomy cause a lung metastasis?
Nineyears post-hysterectomy, additional lung lesion tissue acquired. Immunostaining revealed full negativity to c-kit and Her2/neu, but mixed negative EGFR results with slightly positive staining of material among muscle cells and not the muscle cells themselves.