How high can ca125 levels go?
High levels of CA 125 (from 125 to 10.000 U/ml and higher) were revealed in 54 from 57 patients (94.7%) with malignant ovarian tumors.
Does high CA 125 always mean cancer?
Does a high CA-125 always mean cancer? No, a high CA-125 does not always mean cancer is present. Generally speaking, the normal range of CA-125 is considered to be 0-35 units/mL, while a level above 35 units/mL is considered to be a high CA-125 level.
What level of ca125 indicates endometriosis?
In clinical practice, 93% of women with a serum CA-125 level of 30 U/mL or higher who have had the diagnoses of adenomyosis, leiomyomas, ovarian tumors, pelvic inflammation, and/or pregnancy ruled out will be shown to have endometriosis on further diagnostic testing.
What happens if CA125 is high?
If your CA 125 level is higher than normal, you may have a benign condition, or the test result could mean that you have ovarian, endometrial, peritoneal or fallopian tube cancer.
Can stress cause an elevated CA 125?
The most popular current theories suggest that CA 125 is synthesized by mesothelial cells in response to stress, which can be either mechanical stress caused by fluid overload, or inflammatory stress instigated by the release of mediators such as TNFα and interleukins [5,6].
What are the benign causes of elevated ca 125 levels?
Endometriosis
What does an elevated ca 125 level mean?
A rising CA 125 level may indicate a return or continued growth of the cancer. A number of normal and noncancerous conditions can cause an elevated CA 125 level, including: None of the major professional organizations recommend using the CA125 as a screening test for those with an average risk of ovarian cancer.
What does an elevated ca 125 mean?
Elevated CA-125 (a protein in the blood that’s associated with ovarian cancer) is most often caused by common, ordinary or benign conditions such as uterine fibroids, ovarian cysts, endometriosis — or even just having your period. Measuring CA-125 is most useful in women with known ovarian cancer,…
What is considered a high c 125 level?
The normal value is less than 35 U/mL. If your CA 125 level is higher than normal, you may have a benign condition, or the test result could mean that you have ovarian, endometrial, peritoneal or fallopian tube cancer.